Cart
sales@molnova.com
Netarsudil mesylate
CAS No. 1422144-42-0
Netarsudil mesylate( —— )
Catalog No. M32785 CAS No. 1422144-42-0
Netarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 302 | Get Quote |
|
| 50MG | 486 | Get Quote |
|
| 100MG | 842 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNetarsudil mesylate
-
NoteResearch use only, not for human use.
-
Brief DescriptionNetarsudil mesylate (AR-13324 mesylate) is a Rho-related protein kinase inhibitor used to study glaucoma and hypertension.
-
DescriptionNetarsudil mesylate (AR-13324 mesylate) is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetROCK
-
RecptorROCK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1422144-42-0
-
Formula Weight645.74
-
Molecular FormulaC30H35N3O9S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (154.86 mM; Ultrasonic )
-
SMILESCS(=O)(O)=O.NC[C@H](C1=CC=C(C=C1)COC(C2=C(C=C(C=C2)C)C)=O)C(NC3=CC4=C(C=NC=C4)C=C3)=O.CS(=O)(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.?
molnova catalog
related products
-
H-1152
H-1152 is a potent specific ATP-competitive and cell permeable ROCK inhibitor (Ki = 1.6 nM).
-
Y-27632 dihydrochlor...
Y-27632 2hydrochloride is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay.
-
Rhodblock 6
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that specifically inhibits Rho kinase activity and the localization of phosphorylated MRLC (Myosin Regulatory Light Chain).
